Could microbes communicate with alien species?

I remember staying up all night reading the "Andromeda Strain" by Michael Crichton. The follow-on movie was for me equally riveting. The term microbe has a pejorative connotation. Speculating sentient capabilities to microbes seems a far stretch. Consider that the extent of the context of microbe "communication" with other species has found expression in the rueful memories of many a tourist and gaunt reality of historical pestilence.
 
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