The decision by Griffin to abandon the ISS in 2010 was inexplicable, and rationalized his cancellation of the Shuttle at the very point when it has become safe and productive. If we cannot learn to be productive in LEO, we certainly cannot be productive on the Moon! ISS requires Shuttle. It will become productive in an economic sense when we construct a new reusable launch system. Until then the practical value of the ISS will be limited to serving as a destination for new launch vehicle development and serving its original purpose, as a catalyst for trust and cooperation between nuclear adversaries. Manned flight BEO with expendable rockets, whether the destination is the moon, Mars, or an asteroid, will not occur, except for the occasional political stunt, because it has no practical value worth the cost.