In democracies such entities [as well as religious entities] are routinely separated from the government under transparent laws and regulations. This avoids e.g. corruption and compromised efficiency while ensuring freedom of speech.
Speaking from inside experience, I can say that the U.S. regulatory agencies are not perfectly shielded from political pressure.
But, they are resistant to it.
And that is what the new administration intends to fight against, this time.
During the previous Trump administration, a new process (new "Schedule F") was introduced and in-progress to change the top levels of Civil Service technical employees from protected status to "serves-at-the-pleasure" status so that they would have to obey the political pressures.
That was stopped by the following (Biden) administration, but will most likely be more fully implemented this time due to the next Trump administration having majorities in both houses of Congress to make any needed changes to the implementing legislation for the agencies and the Civil Service.
However, the lower levels of most of the Federal agencies have employee unions, who will resist political and administrative pressures on those employees. The unions have actually been more effective than the enacted laws in shielding the employees from political pressures.
But, that is not to say that the Civil Service employees in a particular agency do not develop individual internal "cultures" that are never out-of-step with what the public supports in the way of government actions. Don't just assume that something is correct because it is the position of a regulatory agency. That was actually a legal presumption recognized by the courts (called the "Chevron Defense") until it was recently overturned by a U.S. Supreme Court decision.
I am expecting a lot of disruption in Federal agencies. I just hope it does not lead to them becoming as disfunctional as our Congress has become when it is almost evenly split on the political spectrum.