The Drake equation for alien intelligence is more important than ever

The Drake Equation was a conceptual exercise designed to stimulate discussion, not a serious attempt at quantification. It has several factors that cannot be determined ahead of time and range from zero to 1.0.

It basically reduces to "The number of civilizations we can detect is equal to the number of civilizations there are times the percent of those we can detect." A good stimulus for discussion but of little practical value.
An easier to apply equation will be to determine how many planets, rogue objects and moons are easy to seed with frozen ocean vent life. Carbon sources and vents might enable insects. Ocean vents might need metals and some sort of barrier to keep out vacuum across a stadium volume. I'm looking at solid-state parts in micro reactors to model, but I'm also seeing the diversity of vitamins biology is capable of making. You would want to make weeds or toxin species that devour everything, so there is lower life seeding, and then stable eco-system seeding, assuming a few trailer loads of maintenance payloads there at the time of seeding.
The nicest life seems to be that able to signal with light it is ready for sexual meosis, but there might be something even more aesthetic possible.

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