To me, Abiogenesis is an interesting theory on a number of levels. First, the idea that a machine like a cell "just appeared" is amazing. At the simplest level I believe cells need some kind of an enclosure, a metabolic system, and a way to copy themselves and pass along genetic info. Assuming the "detail parts" of those requirements were created in a warm little pond, the self-assembling machine seems a bit tricky.
Time is an issue as well. I don't believe the 3 or 4 billion year old fossils are the simplest of cells. So they must have undergone some evolution. Is a billion or so years enough ?
Of course I don't know the answers.
I am a surfactant chemist, so for me the idea of self assembly presents no problem.
Please bear with me for a minute.
Surfactants = short for surface active agents = agents active at surfaces.
Common example = soap = a hydrocarbon chain of normally 12 to 18 carbon atoms joined to a water souble group. In this case carboxylic acid, often sodium salt.
The whole spectrum exists in the balance between water solubility and oil or fat solubility, known as HLB or hydrophilic lipophilic balance.
Large fatty chain and weak water soluble group = very oil/fat soluble
Small fatty chain and strong water soluble group = very water soluble.
Mostly something between is the useful choice.
Without writing a text book, I am making some simplifications.
They form the basis for detergency because the oil/fat chain dissolves in the oily dirt and the water soluble group takes it into the water = cleans the substrate.
Most surfactants (or the most useful ones), when added to water go to the surface (hence surface active). When there is no more room at the surface they must exist in the bulk water phase. To do this the oily parts come together and thus cause the water soluble groups to interphase with the water. So normally you have a spherical group of surfactant molecules with the oily parts together in the centre and the water soluble groups outside. These spherical groups are called micelles and, as you can see, they self assemble.
Now when you get longer fatty chains (16—18 carbons) they are of comparably lower water solublility, higher oil solubility. They are more at home in lower water content environments. They can first form (intermediate) cylindrical micelles and, eventually structures where the fatty chains locate together side by side and enclose aqueous material inside. The outside can interface with more fatty environments. These may be long tubes, with fatty surfactant walls.
This is what happens in cell walls. They self assemble. This is entropy driven. “Hiding” the oil (in the first example) in the water is more favourable entropically than having bare oil – water interfaces.
This has been a very brief summary but it does show the circumstances in which self assembly occurs and relates it to cell walls in living organisms. You could read about it in one of my books published in the Marcel Dekker Surfactant Science Series. Of course I can't say which here.
Cat