"Biologically, the trip would take quite some numbers of months. No one has yet designed a stable, self contained habitat, which can exist long term without substantial inputs of materials and energy sources."<br /><br />All environments need energy supply, and all small closed environments need periodic replenishment. Complete closure is a futile and unnecessary exercise. <br /><br />EVen the ISS must be frequently resupplied with same. WE have NO long term stable, self contained, sustainable habitats operating on this scale anywhere within human space.<br /><br />The ISS, as I recall, is supplied with energy (propellant, solar power), food, spares, and recycles ~90% of it's water. This is all that is needed for a Mars mission, you just need to ensure adequate supplies of the non recycled components. For food and oxygen that amounts to about 1 kg each per person per day. Water (with 90% recycling) 2.5 kg. A 900 day, 6 man Mars mission would need 5.4 tonnes of food, 5.4 tonnes of oxygen, and 13.5 tonnes of water. A large, but not impossible amount. These quantities can be reduced significantly by using ISRU.<br /><br />"People outside of gravitational fields lose muscle mass and bone calcium. If they do not return to normal gees within several months, the NASA limit is 4 mos., there is NO full return to normal earth gravity functioning. They suffer life long disabilities."<br /><br />The NASA limit is not 4 months, the standard stint of the space station is 6 months. The record is 14 months (not my NASA). There is rapid return to full 1G function (a few days to weeks), people have flown multiple long duration missions, and do not suffer life long disabilities.<br /><br />"Weightless re-hardwires the brain's balance system, which upon return to normal gravity interprets head movements as accelerations at a high rate, which are very disorienting. It takes weeks to months to re-hardwire the system on earth return and the longer one is is space, the less complete this re- <div class="Discussion_UserSignature"> <p><em>Whether we become a multi-planet species with unlimited horizons, or are forever confined to Earth will be decided in the twenty-first century amid the vast plains, rugged canyons and lofty mountains of Mars</em> Arthur Clarke</p> </div>