There are actually quite a lot of space-related games out there. One that I found particularly interesting was Apollo XIII, which has players simulating the events of the Apollo 13 difficulties and attempting to get the astronauts safely home.
Another I'd like to tell you about is Astronomy Fluxx by Looney Labs (I work for them). It just released January 9th, and is an entertaining and educational card game featuring beautiful NASA photography on black backgrounds and a fun game mechanism where the rules are constantly changing... in Fluxx. I hope you'll give it a try!
If you prefer sci-fi, we have several versions of Fluxx for Star Trek fans--Original Series, Next Generation, and Deep Space Nine, with Voyager coming out later this year. But the coolest game we have for Star Trek fans is Star Trek: Chrono-Trek, a time travel game that covers the entire Star Trek universe!
We've also got Firefly Fluxx and Space Fluxx (a spoof on a variety of space TV shows and movies). We're a little heavy on space related titles because our founders, Kristin and Andy Looney, used to be NASA engineers.
Finally, if you'd like to find a LOT more space-related games, I suggest going to boardgamegeek.com and typing "space" or "astronomy" or "astronaut" into the search. There are dozens to choose from. Enjoy!