During WWII all the warring nations tried to keep away from obvert use of chemical and biological weapons. Since WWII, during the Cold War conflicts use of nuclear weapons has been added to use of the other two (thus CBN) to stay away from during major power conflict.
Above, I liked what Dr. Sharma had to say, but life is inherently conflict, minor and major, and some point the minor will build, or complexity collapse, inevitably to the major. Some of you have heard the saying of piling straw (straws) on the camel's back and it will be the weight of the last least littlest needle of straw's complexity that will break the camel's back.
It's a matter of negative entropies, a matter of buildup of least little tyrannies, wars of a thousand (million, billion) least littlest cuts, into the force of major Iron Curtain bubble tyrannies, major darkening unraveling of civilizations, enclosed closed or closing systematic entropies, that will have rotted the aging (Orwellian Utopian Dystopian) structures and infrastructure of governments and civilization to brittle stone-poor facsimiles of what was. Ancient Greco-Roman and Chinese civilizations did not ultimately decline and fall from the pressures of external barbarism but from growing nonsense barbarisms and losses of dynamic history within.
My answer! No matter what you think the cost will be, breakout in a spreading out to more or less local area networks (LANs) and wide area networks (WANs) of detached environmentally shielded and protected Personal Colony ((space colony 'Space Ark') PCs)) Space Frontier Colonization. Else, Stephen Hawking's prophecy of 1,000 years to Mankind's extinction (if breakout doesn't happen), and maybe all life's extinction on the Earth, will have been far too optimistic!