Seems like a fairly open question. Also, I am not sure a "moon base" has been explicitly stated in the vision.<br /><br />Some of the issues include: How many people will be included; will they stay there only during daylight period (approx 2 weeks) or will they be there for the approx 2 weeks of night time (energy issues); how closed are their life support systems; what type of work will they be doing there; will they be returning any mass other than themselves; what type of technologies will be used to move between the earth and moon; and so on.<br /><br />Zubrin came up with some good estimates for Mars, but his plan included "living off the land". Still, a good closed-loop life support system could compensate to some extent. Get his "Case for Mars" book and look at some of the details.