I’ll never say never… HOWEVER…. I'm going to play pessimist here. Life? Probably. Intelligent life like us on a scale capable of what our homo sapiens brains have become, or greater? Doubtful. Physics, chemistry, biology, and the formations of solar systems are pretty uniform across the universe as far as we know.
Here on Earth, there have been 12 extinction events and five of those were major ones. If any of those five don’t happen, we’re not here. If one of those other seven don’t happen, it’s also probable we’re not here.
BEFORE ALL THAT THOUGH... If there wasn’t the planetary collision that formed the moon that slowed down Earth’s rotation, we’re not here. If the moon didn’t generally settle at its current distance to create our current tide levels, thusly creating the inter-tidal zone where life began to move from the sea to the land, we’re not here. If we don’t have our axial tilt from that collision which created our seasons, we’re not here. In the early formation of the solar system, Jupiter made its way to the inner solar system but was pulled back out by Saturn. If there’s no Saturn to do that, Earth, if it wasn't destroyed, wouldn't settle in the habitable zone, and we’re not here. If Jupiter and Saturn weren’t out there to protect us from a bombardment of asteroids and comets, we’re not here. Yet if we didn’t have the right amount of those asteroids and comets hit Earth to bring us the right amount of water, microbes, and elements to start life, we’re not here. If we didn’t have that one asteroid that also got through and wiped out the dinosaurs (the last of the five major extinction events) leading to the evolution of mammals, we’re not here.
If our Hominid lineage didn’t split from chimps 6-7 million years ago, we’re not here. Even that lineage was still pretty ape-like for the next 3-4 million years. If even one of those subsequent Homo mutations/evolution events doesn’t take place, we’re not here. For us, it took 4.5 billion years to become the intelligent species we are, and we had to go through a GAUNTLET of if/thens to become the Homo Sapiens species we are. The odds of that happening again are slim at best. If Earth formed 24 hours ago, hominids appeared at 23:58. That’s not even Homo Sapiens which came much later. Dinosaurs only died out about 23:30.
Yes there may be millions, billions, trillions of “habitable” planets out there, and there’s nothing to say that intelligent life can’t or wouldn’t develop in other ways. It probably would. But when you look at what had to happen to Earth in those 23 hours and 58 minutes to become a “hospitable” planet for not only life, but intelligent life, along with the combination of the extinction and evolution events for us to develop/evolve into that intelligent life, the right and stable atmosphere to continually support developing life, and have the proper growth of land and sea plant life over 4.5 billion years to sustain that atmosphere which sustains said life, it doesn’t look promising that there is other intelligent life out there on our scale or greater no matter how that life is formed and subsequently develops.